Claire would be kidnapped by Alex Wesker, another evil Umbrella experimental subject, before escaping and destroying a new Wesker. Later, Claire is seen working with a non-profit organization in Resident Evil: Revelations 2 some time between the events of Resident Evil 5 and 6. Chris eventually rescues his sister and the two vow to destroy the nefarious corporation once and for all. After escaping the island with the help of fellow prisoner Steve Burnside, Claire finally reunites with her brother only to be captured by Umbrella once again and detained in a secret lab in Antartica.
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Still searching for her brother, Claire would next be seen in 2000's Resident Evil: Code Veronica, where she was imprisoned on Rockfort Island by Umbrella after investigating one of its facilities in Paris three months after the events of Resident Evil 2. RELATED: Resident Evil 2 is Much More Than Just a Remake After being separated from rookie cop Leon Kennedy, Claire makes her way through the police precinct where Chris worked, ultimately escaping the city through an underground Umbrella science facility before the entire town is destroyed by the military in an attempt to contain the virus.
Soon after, the entire city becomes overrun by zombies as the Umbrella Corporation's T-Virus sweeps across the Midwestern metropolis with those infected transforming into ravenous undead monsters. When she debuted in 1998's Resident Evil 2, Claire arrives in Raccoon City looking for Chris, who went missing during the events of the first Resident Evil.